Tirzepatide: which line to draw to
Enter your Tirzepatide vial amount, the water you added and your dose. Tirzepatide is dosed in mg; the syringe shows exactly where to stop. New to this?
Your line shows up here.
Fill in the vial, water and dose boxes.
Approved drug. Sold as Mounjaro and Zepbound.
Tirzepatide at a glance
- Evidence
- Approved drug. Sold as Mounjaro and Zepbound.
- Vial sizes
- 5, 10, 15, 30 mg
- Usual dose range
- 2.5–15 mg
- How often
- Weekly
- Unmixed
- Freezer −20°C
- After mixing
- Fridge 2–8°C, use within 28 days
Tirzepatide units to mg chart
Syringe units on any U-100 insulin syringe (100 units = 1 mL), worked out by the same engine as the calculator. Your own vial and water may differ: use the calculator for your numbers.
| Dose | Units | mL |
|---|---|---|
| 2.5 mg | 100 | 1 |
| 5 mg | More than a 1 mL syringe | |
| 7.5 mg | More than the vial holds | |
| 10 mg | More than the vial holds | |
| 12.5 mg | More than the vial holds | |
| 15 mg | More than the vial holds | |
| Dose | Units | mL |
|---|---|---|
| 2.5 mg | 50 | 0.5 |
| 5 mg | 100 | 1 |
| 7.5 mg | More than a 1 mL syringe | |
| 10 mg | More than a 1 mL syringe | |
| 12.5 mg | More than the vial holds | |
| 15 mg | More than the vial holds | |
| Dose | Units | mL |
|---|---|---|
| 2.5 mg | 50 | 0.5 |
| 5 mg | 100 | 1 |
| 7.5 mg | More than a 1 mL syringe | |
| 10 mg | More than a 1 mL syringe | |
| 12.5 mg | More than a 1 mL syringe | |
| 15 mg | More than a 1 mL syringe | |
| Dose | Units | mL |
|---|---|---|
| 2.5 mg | 25 | 0.25 |
| 5 mg | 50 | 0.5 |
| 7.5 mg | 75 | 0.75 |
| 10 mg | 100 | 1 |
| 12.5 mg | More than a 1 mL syringe | |
| 15 mg | More than a 1 mL syringe | |
Tirzepatide questions
How many units is 2.5 mg of Tirzepatide?
With a 5 mg vial mixed with 2 mL of bacteriostatic water, 2.5 mg is 100 units (1 mL) on a U-100 insulin syringe. A different vial size or amount of water changes this, so check it with your own numbers.
How much water do I add to a 5 mg Tirzepatide vial?
2 mL of bacteriostatic water is common, which makes 2.5 mg per mL. More water makes each dose a bigger amount that is easier to measure; it doesn't change how much is in the vial.
How long does mixed Tirzepatide last?
Once mixed, keep it at fridge temperature, 2–8°C and use it within 28 days. Unmixed powder: freezer −20°c.
What is Tirzepatide?
Tirzepatide is approved as Mounjaro for type 2 diabetes and as Zepbound for weight management. It copies two gut hormones, GLP-1 and GIP, where semaglutide copies one. In SURMOUNT-1, people on 15 mg a week lost about 21% of their body weight on average over 72 weeks.
Vial size changes everything
Tirzepatide vials range from 5 to 30 mg, so the same number of units can be a very different dose. A 30 mg vial mixed with 3 mL of water is four times stronger than a 5 mg vial mixed with 2 mL. Always work the dose out from your own vial and the water you added.
Stepping up
The approved schedule starts at 2.5 mg once a week and goes up by 2.5 mg no faster than every 4 weeks, to at most 15 mg. Many people stay on a lower dose; that’s a decision for you and your prescriber.
What to watch for
The common side effects are the same as semaglutide’s: nausea, diarrhoea and constipation, mostly after a dose goes up. Severe stomach pain that doesn’t go away needs medical help. Tirzepatide can also make the contraceptive pill less reliable for 4 weeks after starting and after each dose increase.
Sources
- Jastreboff AM et al. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med, 2022.